Integrated Drug Discovery Service
Our experienced research teams can help achieve the following:
 Compound design and synthesis to improve potency and selectivity.
 Develop structure activity relationships (SAR).


Chemistry service
Organic synthesis
ZB CHEM provides the following types of discovery chemistry services

• Custom Synthesis (> 95% purity, milligrams to kilograms scale) 
• Designed compounds for SAR studies 
• Reference compounds 
• Building blocks & scaffolds 
• Key and advanced intermediates 
• Synthetic pathway design, evaluation and scouting

Medicinal chemistry
ZB CHEM provides the following types of discovery chemistry services

• Active assessment Synthesis and confirmation of actives
• Active-to-hit exploration
• Novelty assessment
• Competitor analysis
• Lead optimization
• SAR development

Process chemistry R&D

• Route evaluation and development of new synthetic routes for target molecules.
• Optimization of reaction conditions to reduce cost and maximize throughput
• Development of reliable methods for in-process testing and analysis of intermediates and API’s.
• Scale-up of existing routes in jacketed glass reactors (30-100 L) and fixed reactors (up to 1000 L capacity)
• Performance of work under cryogenic conditions (-78 °C)
• Assessment of critical process parameter
• Development and transfer of analytical methods
• Kilo lab / Pilot plant manufacturing APIs & Intermediates under GMP or cGMP.